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The bidirectional regulation mechanism between the brain and the gut, namely the microbiota-gut-brain(MGB) axis, has become a hot field of neuroscience research

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Furthermore, it has also been demonstrated that hypoxia-driven CSC enrichment in breast cancer originates from a dedifferentiation process and that hypoxia-inducible factors (HIFs) are essential for chemotherapy resistance in breast CSCs ( 8 Strategies to Overcome Breast Cancer Resistance 8.1 Endogenous Molecule Inhibitors Various endogenous molecules, such as E-cadherin (Kim WD